Archaeal tetraether bipolar lipids: Structures, functions and applications

Biochimie. 2009 Jun;91(6):711-7. doi: 10.1016/j.biochi.2009.01.006.


Archaea have developed specific tools permitting life under harsh conditions and archaeal lipids are one of these tools. This microreview describes the particular features of tetraether-type archaeal lipids and their potential applications in biotechnology. Natural and synthetic tetraether lipid structures as well as their applications in drug/gene delivery, vaccines and proteoliposomes or as lipid films are reviewed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Archaea / chemistry*
  • Archaea / metabolism*
  • Biotechnology / methods
  • Biotechnology / trends
  • Lipid Metabolism / physiology*
  • Lipids / chemical synthesis
  • Lipids / chemistry*
  • Molecular Structure


  • Lipids