Chronic pelvic pain syndromes: clinical, urodynamic, and urothelial observations

Int Urogynecol J Pelvic Floor Dysfunct. 2009 Sep;20(9):1047-53. doi: 10.1007/s00192-009-0897-7. Epub 2009 May 21.

Abstract

Introduction/methods: A cohort of 408 patients with bladder pain syndrome/interstitial cystitis (BPS/IC) was evaluated, and findings were discussed in this retrospective chart review.

Results: Based on the chief complaints, they were divided into four subgroups: BPS/IC (n = 157), CPP (n = 98), vulvodynia/dyspareunia (n = 40), and "other" (n = 113). Similar findings were found in all four subgroups: complaints of voiding dysfunction (70%), dyspareunia (54%), mean PUF score of 15.9 +/- 6.4, and a positive potassium sensitivity test in 83%. Urodynamics revealed a maximal urethral pressure of 131 cm of water and an abnormal uroflow in 80%. Urothelial therapy in the form of intravesical therapeutic anesthetic cocktails provided benefit in all groups (50%, 67%, 73%, and 77% for vulvodynia, CPP, BPS/IC, "other").

Conclusions: All subgroups had similar findings and response to therapy. Five to 10% of patients with chief complaints of stress or urge incontinence or prolapse were also found to have BPS/IC.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Cohort Studies
  • Cystitis, Interstitial / complications*
  • Cystitis, Interstitial / diagnosis*
  • Dyspareunia / complications*
  • Female
  • Humans
  • Middle Aged
  • Pelvic Pain / complications*
  • Retrospective Studies
  • Urinary Incontinence / complications*
  • Young Adult