Lipophagy: selective catabolism designed for lipids

Dev Cell. 2009 May;16(5):628-30. doi: 10.1016/j.devcel.2009.05.001.


Until recently, degradation of lipid droplets (LDs) has been thought to take place in the cytosol by resident lipases. In a recent issue of Nature, Singh and coworkers describe the involvement of selective autophagy in the delivery of lipid droplets for lysosomal degradation.

MeSH terms

  • Animals
  • Autophagy*
  • Cytosol / metabolism
  • Lipolysis*
  • Lysosomes / metabolism
  • Mice