Mammalian macroautophagy at a glance

doi:10.1242/jcs.031773

Review

. 2009 Jun 1;122(Pt 11):1707-11.

doi: 10.1242/jcs.031773.

Mammalian macroautophagy at a glance

Brinda Ravikumar¹, Marie Futter, Luca Jahreiss, Viktor I Korolchuk, Maike Lichtenberg, Shouqing Luo, Dunecan C O Massey, Fiona M Menzies, Usha Narayanan, Maurizio Renna, Maria Jimenez-Sanchez, Sovan Sarkar, Benjamin Underwood, Ashley Winslow, David C Rubinsztein

Affiliations

PMID: 19461070
PMCID: PMC2684830
DOI: 10.1242/jcs.031773

Free PMC article

Review

Mammalian macroautophagy at a glance

Brinda Ravikumar et al. J Cell Sci. 2009.

Free PMC article

. 2009 Jun 1;122(Pt 11):1707-11.

doi: 10.1242/jcs.031773.

Authors

Affiliation

¹ Department of Medical Genetics, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0XY, UK.

PMID: 19461070
PMCID: PMC2684830
DOI: 10.1242/jcs.031773

No abstract available

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References

1. Axe, E. L., Walker, S. A., Manifava, M., Chandra, P., Roderick, H. L., Habermann, A., Griffiths, G. and Ktistakis, N. T. (2008). Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J. Cell Biol. 182, 685-701. - PMC - PubMed
1. Chan, E. Y., Longatti, A., McKnight, N. C. and Tooze, S. A. (2009). Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism. Mol. Cell. Biol. 29, 157-171. - PMC - PubMed
1. Ding, W. X., Ni, H. M., Gao, W., Yoshimori, T., Stolz, D. B., Ron, D. and Yin, X. M. (2007). Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am. J. Pathol. 171, 513-524. - PMC - PubMed
1. Eskelinen, E. L., Illert, A. L., Tanaka, Y., Schwarzmann, G., Blanz, J., Von Figura, K. and Saftig, P. (2002). Role of LAMP-2 in lysosome biogenesis and autophagy. Mol. Biol. Cell 13, 3355-3368. - PMC - PubMed
1. Fujita, N., Itoh, T., Omori, H., Fukuda, M., Noda, T. and Yoshimori, T. (2008). The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol. Biol. Cell 19, 2092-2100. - PMC - PubMed

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[1] Axe, E. L., Walker, S. A., Manifava, M., Chandra, P., Roderick, H. L., Habermann, A., Griffiths, G. and Ktistakis, N. T. (2008). Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J. Cell Biol. 182, 685-701. - PMC - PubMed

[2] Axe, E. L., Walker, S. A., Manifava, M., Chandra, P., Roderick, H. L., Habermann, A., Griffiths, G. and Ktistakis, N. T. (2008). Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J. Cell Biol. 182, 685-701. - PMC - PubMed

[3] Chan, E. Y., Longatti, A., McKnight, N. C. and Tooze, S. A. (2009). Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism. Mol. Cell. Biol. 29, 157-171. - PMC - PubMed

[4] Chan, E. Y., Longatti, A., McKnight, N. C. and Tooze, S. A. (2009). Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism. Mol. Cell. Biol. 29, 157-171. - PMC - PubMed

[5] Ding, W. X., Ni, H. M., Gao, W., Yoshimori, T., Stolz, D. B., Ron, D. and Yin, X. M. (2007). Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am. J. Pathol. 171, 513-524. - PMC - PubMed

[6] Ding, W. X., Ni, H. M., Gao, W., Yoshimori, T., Stolz, D. B., Ron, D. and Yin, X. M. (2007). Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am. J. Pathol. 171, 513-524. - PMC - PubMed

[7] Eskelinen, E. L., Illert, A. L., Tanaka, Y., Schwarzmann, G., Blanz, J., Von Figura, K. and Saftig, P. (2002). Role of LAMP-2 in lysosome biogenesis and autophagy. Mol. Biol. Cell 13, 3355-3368. - PMC - PubMed

[8] Eskelinen, E. L., Illert, A. L., Tanaka, Y., Schwarzmann, G., Blanz, J., Von Figura, K. and Saftig, P. (2002). Role of LAMP-2 in lysosome biogenesis and autophagy. Mol. Biol. Cell 13, 3355-3368. - PMC - PubMed

[9] Fujita, N., Itoh, T., Omori, H., Fukuda, M., Noda, T. and Yoshimori, T. (2008). The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol. Biol. Cell 19, 2092-2100. - PMC - PubMed

[10] Fujita, N., Itoh, T., Omori, H., Fukuda, M., Noda, T. and Yoshimori, T. (2008). The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol. Biol. Cell 19, 2092-2100. - PMC - PubMed

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Mammalian macroautophagy at a glance

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Mammalian macroautophagy at a glance

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