Mammalian epididymal proteome

Mol Cell Endocrinol. 2009 Jul 10;306(1-2):45-50. doi: 10.1016/j.mce.2009.03.007. Epub 2009 Mar 25.


In all mammalian species, the final differentiation of the male germ cell occurs in the epididymal duct where the spermatozoa develop the ability to be motile and fertilize an ovum. Understanding of these biological processes is the key to understanding and controlling male fertility. Comparative studies between several mammals could be an informative approach to finding common sperm modifications which are not species-specific. The new global biological approaches such as transcriptomes and proteomes provide considerable information which can be used for such comparative approaches. This report summarizes our proteomic studies of the epididymis of several mammals, including humans.

Publication types

  • Review

MeSH terms

  • Animals
  • Body Fluids / metabolism
  • Epididymis / metabolism*
  • Humans
  • Male
  • Mammals / metabolism*
  • Proteome / metabolism*
  • Species Specificity
  • Sperm Maturation


  • Proteome