Lymphoid organs for peritoneal cavity immune response: milky spots

Immunity. 2009 May;30(5):670-2. doi: 10.1016/j.immuni.2009.04.005.

Abstract

Milky spots are located in the omentum of the peritoneal cavity and their classification as lymphoid organs has been debated. In this issue of Immunity, Rangel-Moreno et al. (2009) provide compelling data to consider them as unique secondary lymphoid organs.

Publication types

  • Comment

MeSH terms

  • Animals
  • B-Lymphocyte Subsets / immunology*
  • B-Lymphocyte Subsets / metabolism
  • Chemokine CXCL13 / genetics
  • Chemokine CXCL13 / immunology*
  • Lymphoid Tissue / immunology*
  • Lymphoid Tissue / metabolism
  • Lymphotoxin-alpha / genetics
  • Lymphotoxin-alpha / immunology*
  • Mice
  • Mice, Knockout
  • Omentum / immunology*
  • Omentum / metabolism
  • Peritoneal Cavity*

Substances

  • Chemokine CXCL13
  • Lymphotoxin-alpha