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. 2009 May 26;19(10):R407-9.
doi: 10.1016/j.cub.2009.03.058.

Oxygen Sensation: Into Thick Air

Free PMC article

Oxygen Sensation: Into Thick Air

Mark J Alkema. Curr Biol. .
Free PMC article


Two recent studies show that a neural globin tunes oxygen responses in the nematode Caenorhabditis elegans. Analysis of wild C. elegans strains suggests that the commonly used Bristol strain may have adapted to life in the laboratory.


Figure 1
Figure 1. C. elegans ’ journey from the compost heap to the agar plate has subjected it to different selective pressure
Polymorphisms in the neuropeptide receptor gene npr-1 and the neural globin gene glb-5 may have provided the common laboratory strain Bristol N2 a selective advantage to life at high oxygen levels.

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