Relationship of depression and cognitive impairment to self-injury in borderline personality disorder, major depression, and schizophrenia

Psychiatry Res. 1991 Jul;38(1):77-87. doi: 10.1016/0165-1781(91)90054-s.


Self-injury was studied in 64 adults with borderline personality disorder, major depression, or chronic paranoid schizophrenia. Subjects were rated according to acute depression, chronic depression, self-injurious behaviors, and neurocognitive deficits, as measured by cognitive function examination. Borderline patients showed more self-injurious behaviors and more chronic depressive symptoms than the major depression or schizophrenia groups. Self-injury was not significantly correlated with acute or chronic depression in any group, but self-injury was correlated with neurocognitive deficits in borderline and schizophrenic groups. The results are explained in the context of a neurocognitive model of psychotic thought process in borderline disorder and schizophrenia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptation, Psychological*
  • Adolescent
  • Adult
  • Borderline Personality Disorder / diagnosis*
  • Borderline Personality Disorder / psychology*
  • Cognition Disorders / diagnosis*
  • Cognition Disorders / psychology*
  • Depressive Disorder / diagnosis*
  • Depressive Disorder / psychology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neurocognitive Disorders / diagnosis
  • Neurocognitive Disorders / psychology
  • Neuropsychological Tests / statistics & numerical data
  • Psychiatric Status Rating Scales / statistics & numerical data
  • Psychometrics
  • Schizophrenia, Paranoid / diagnosis*
  • Schizophrenic Psychology*
  • Self Mutilation / diagnosis*
  • Self Mutilation / psychology*
  • Thinking