Performance of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) as a screening test for dementia

Psychol Med. 1991 Aug;21(3):785-90. doi: 10.1017/s0033291700022418.


A 26-item informant questionnaire (IQCODE) and the Mini-Mental State Examination (MMSE) were compared as screening tests for dementia in a sample of 69 patients. Dementia diagnoses were made by both a clinician and a research interview using a computer algorithm to meet DSM-III-R and ICD-10 (Draft) criteria. The IQCODE was found to perform at least as well as the MMSE against all diagnoses and significantly better when judged against the algorithmic ICD-10 diagnoses. Also, the IQCODE was found to be uncontaminated by pre-morbid ability as estimated from the National Adult Reading Test and to have very high test-retest reliability after a delay of a day or more.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aptitude
  • Cognition Disorders / diagnosis*
  • Cognition Disorders / psychology*
  • Dementia / diagnosis*
  • Dementia / psychology*
  • Female
  • Humans
  • Male
  • Mental Status Schedule / statistics & numerical data*
  • Middle Aged
  • Neuropsychological Tests / statistics & numerical data*
  • Psychometrics
  • ROC Curve