Abstract
The aim of this study was to assess changes in serum concentrations of C-reactive protein (CRP), serum amyloid A component (SAA), and haptoglobin (Hp) in bitches with pyometra undergoing ovariohysterectomy that developed postoperative wound infection-related complications. The study revealed that difficulties in postoperative wound healing were induced by infections with Escherichia coli and Staphylococcus spp. leading to re-increased levels of CRP and SAA immediately after surgery and persistently high Hp levels throughout the experiment. Our results indicate that acute-phase proteins in bitches undergoing surgery because of pyometra are useful markers for monitoring the postoperative period. Moreover, they enable prompt therapeutic management once complications develop.
MeSH terms
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Animals
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Biomarkers / metabolism
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C-Reactive Protein / metabolism*
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Dog Diseases / diagnosis
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Dog Diseases / microbiology
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Dog Diseases / surgery*
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Dogs
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Escherichia coli Infections / complications
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Escherichia coli Infections / diagnosis
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Escherichia coli Infections / veterinary
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Female
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Haptoglobins / metabolism*
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Hysterectomy / veterinary
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Ovariectomy / veterinary
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Postoperative Care / veterinary
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Pyometra / surgery
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Pyometra / veterinary*
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Serum Amyloid A Protein / metabolism*
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Staphylococcal Infections / complications
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Staphylococcal Infections / diagnosis
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Staphylococcal Infections / veterinary
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Surgical Wound Infection / diagnosis
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Surgical Wound Infection / microbiology
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Surgical Wound Infection / veterinary*
Substances
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Biomarkers
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Haptoglobins
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Serum Amyloid A Protein
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C-Reactive Protein