Comments on the Course and Classification of Lyme Borreliosis

Scand J Infect Dis Suppl. 1991;77:41-3.


On the basis of answers by clinicians to a questionnaire concerning the classification and staging of Lyme borreliosis, the following classification is proposed: EARLY LYME BORRELIOSIS Localized infection: Erythema migrans and borrelial lymphocytoma without signs or symptoms of disseminated infection. (Regional lymphadenopathy and/or minor constitutional symptoms may be present). Early disseminated infection: Multiple erythema migrans-like skin lesions. Early manifestations of neuroborreliosis, arthritis, carditis or other organ involvement. LATE LYME BORRELIOSIS Chronic infection: Acrodermatitis chronica atrophicans. Neurologic, rheumatic or other organ manifestations--persistent or remitting for at least 12 (or 6) months.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Erythema Chronicum Migrans / etiology*
  • Humans
  • Lyme Disease / etiology*