IMP dehydrogenase: structure, mechanism, and inhibition

Chem Rev. 2009 Jul;109(7):2903-28. doi: 10.1021/cr900021w.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Catalytic Domain
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology
  • Humans
  • IMP Dehydrogenase / antagonists & inhibitors*
  • IMP Dehydrogenase / chemistry
  • IMP Dehydrogenase / metabolism
  • Kinetics
  • Neoplasms / enzymology
  • Protein Structure, Tertiary
  • Substrate Specificity

Substances

  • Enzyme Inhibitors
  • IMP Dehydrogenase