Reactive arthritis: clinical aspects and medical management

Rheum Dis Clin North Am. 2009 Feb;35(1):21-44. doi: 10.1016/j.rdc.2009.03.010.

Abstract

Reactive arthritis (ReA) is an inflammatory arthritis that arises after certain gastrointestinal or genitourinary infections, representing a classic interplay between host and environment. It belongs to the group of arthritidies known as the spondyloarthropathies. The classic syndrome is a triad of symptoms, including the urethra, conjunctiva, and synovium; however, the majority of patients do not present with this triad. Diagnostic criteria for ReA exist, but data suggest new criteria are needed. Epidemiologic and prospective studies have been difficult to perform because of over-reliance on the complete classic triad of symptoms and the different terms and eponyms used. Studies assessing various treatment strategies are ongoing.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Arthritis, Reactive / diagnosis*
  • Arthritis, Reactive / drug therapy
  • Arthritis, Reactive / microbiology
  • Arthritis, Reactive / physiopathology
  • Campylobacter / pathogenicity
  • Campylobacter / physiology
  • Campylobacter Infections / complications
  • Campylobacter Infections / drug therapy
  • Campylobacter Infections / physiopathology
  • Chlamydia / pathogenicity
  • Chlamydia / physiology
  • Chlamydia Infections / complications
  • Chlamydia Infections / drug therapy
  • Chlamydia Infections / physiopathology
  • Dysentery, Bacillary / complications
  • Dysentery, Bacillary / drug therapy
  • Dysentery, Bacillary / physiopathology
  • Host-Pathogen Interactions
  • Humans
  • Salmonella / pathogenicity
  • Salmonella / physiology
  • Salmonella Infections / complications
  • Salmonella Infections / drug therapy
  • Salmonella Infections / physiopathology
  • Shigella / pathogenicity
  • Shigella / physiology
  • Yersinia / pathogenicity
  • Yersinia / physiology
  • Yersinia Infections / complications
  • Yersinia Infections / drug therapy
  • Yersinia Infections / physiopathology

Substances

  • Anti-Bacterial Agents