Primary gait ignition disorder: report of three cases

Neurol Sci. 2009 Aug;30(4):333-7. doi: 10.1007/s10072-009-0093-z. Epub 2009 May 30.

Abstract

Gait ignition failure (GIF) classifications all had major limitations. Few years ago, a new and simpler classification was proposed by Liston. The aim of this paper is to discuss three GIF patients with respect to this new classification. All three patients presented with hesitation to start walking and turning and their neurological examination revealed start and turn hesitation without any other abnormality. We classified our patients according to Liston's classification as ignition apraxia, which enabled us to approach the patients in a practical way. This classification helps to understand the underlying pathologies and combines clinical characteristics and pathophysiology. We reported our experience with pergolide in the treatment of patients suffering from primary GIF and underline the fact that more research is needed on the treatment of this condition.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angiotensin-Converting Enzyme Inhibitors / therapeutic use
  • Antiparkinson Agents / therapeutic use
  • Atrophy
  • Brain / pathology
  • Fosinopril / therapeutic use
  • Gait Apraxia / classification
  • Gait Apraxia / physiopathology*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Neurologic Examination
  • Neuroprotective Agents / therapeutic use
  • Neuropsychological Tests
  • Pergolide / therapeutic use

Substances

  • Angiotensin-Converting Enzyme Inhibitors
  • Antiparkinson Agents
  • Neuroprotective Agents
  • Pergolide
  • Fosinopril