Adults with Tourette's syndrome with and without attention deficit hyperactivity disorder

Acta Psychiatr Scand. 2009 Oct;120(4):299-307. doi: 10.1111/j.1600-0447.2009.01398.x. Epub 2009 Apr 15.

Abstract

Objective: Comorbidity between Tourette's syndrome (TS) and attention deficit hyperactivity disorder (ADHD) is high. In children, those with both TS+ADHD fare less well than those with TS-only on measures of both psychopathology and behaviour. The objective of this study was to document such measures in adult patients.

Method: Eighty adults with TS-only were compared to 64 with TS+ADHD using a clinical interview and standardised measures of depression, anxiety and obsessionality.

Results: The two groups were no different on measures of TS severity. TS+ADHD patients had significantly more depression, anxiety, obsessive-compulsive behaviour and maladaptive behaviours than patients with TS-only. There were also significant differences in the incidence of copro- and echo-phenomena and family history of ADHD.

Conclusion: The finding of increased overall behavioural difficulties and psychopathology in adult patients with TS+ADHD when compared with TS-only is in agreement with previous findings in children with TS. Appropriate treatment of ADHD in TS patients during childhood may prevent many behavioural problems in adulthood.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anxiety Disorders / diagnosis
  • Anxiety Disorders / epidemiology
  • Anxiety Disorders / psychology
  • Attention Deficit Disorder with Hyperactivity / diagnosis
  • Attention Deficit Disorder with Hyperactivity / epidemiology*
  • Comorbidity
  • Diagnostic and Statistical Manual of Mental Disorders
  • Disruptive, Impulse Control, and Conduct Disorders / diagnosis
  • Disruptive, Impulse Control, and Conduct Disorders / epidemiology
  • Female
  • Humans
  • Male
  • Prevalence
  • Severity of Illness Index
  • Surveys and Questionnaires
  • Tourette Syndrome / diagnosis
  • Tourette Syndrome / epidemiology*
  • Tourette Syndrome / psychology
  • Young Adult