Serious complications of cosmetic NewColorIris implantation

Acta Ophthalmol. 2010 Sep;88(6):700-4. doi: 10.1111/j.1755-3768.2008.01499.x.


Purpose: This case report describes serious postoperative complications and markedly elevated intraocular pressure (IOP) associated with the NewColorIris cosmetic implant.

Methods: We report an interventional case series of two patients who suffered multiple complications after NewColorIris implantation carried out in Panama. Assessment included visual acuity, photography, endothelial cell count and anterior segment optical coherence tomography (OCT) when possible.

Results: Both patients presented with endothelial cell loss, uveitis, pigment dispersion and elevated IOP. Anterior segment OCT demonstrated irregularities in the position and configuration of the implants within the anterior chamber with resultant areas of implant-iris and implant-endothelial contact. One patient had acute postoperative hyphaema that resolved with anterior chamber tissue plasminogen activator injection. Both patients required explantation OU, one eye has required trabeculectomy, and one eye with bullous keratopathy is being evaluated for Descemet's stripping endothelial keratoplasty.

Conclusions: Implantation of the NewColorIris cosmetic implant can lead to serious complications including hyphaema, uncontrolled IOP, severe endothelial cell loss, bullous keratopathy and anterior uveitis. Explantation may lead to improvement, but permanent damage to the trabecular meshwork and corneal endothelium persists.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anterior Chamber / surgery*
  • Cell Count
  • Corneal Endothelial Cell Loss / etiology*
  • Cosmetic Techniques / adverse effects*
  • Device Removal
  • Endothelium, Corneal / pathology
  • Female
  • Humans
  • Intraocular Pressure
  • Ocular Hypertension / etiology*
  • Postoperative Complications*
  • Prostheses and Implants / adverse effects*
  • Prosthesis Implantation
  • Tomography, Optical Coherence
  • Uveitis / etiology*