An assessment of the long-term health outcome of renal transplant recipients in Ireland

Ir J Med Sci. 2009 Dec;178(4):407-12. doi: 10.1007/s11845-009-0363-z.

Abstract

Background: Renal transplantation remains the preferred method of renal replacement therapy in terms of patient survival, quality of life and cost. However, patients have a high risk of complications ranging from rejection episodes, infection and cancer, amongst others.

Aims and methods: In this study, we sought to determine the long-term health outcomes and preventive health measures undertaken for the 1,536 living renal transplant patients in Ireland using a self-reported questionnaire. Outcomes were divided into categories, namely, general health information, allograft-related information, immunosuppression-related complications and preventive health measures.

Results: The results demonstrate a high rate of cardiovascular, neoplastic and infectious complications in our transplant patients. Moreover, preventive health measures are often not undertaken by patients and lifestyle choices can be poor.

Conclusions: This study highlights the work needed by the transplantation community to improve patient education, adjust immunosuppression where necessary and aggressively manage patient risk factors.

MeSH terms

  • Cardiovascular Diseases / epidemiology
  • Female
  • Fertility
  • Health Behavior*
  • Health Status*
  • Health Surveys
  • Humans
  • Immunosuppression Therapy / adverse effects
  • Infections / epidemiology
  • Ireland / epidemiology
  • Kidney Transplantation / adverse effects*
  • Kidney Transplantation / immunology
  • Male
  • Middle Aged
  • Neoplasms / epidemiology
  • Osteoporosis / epidemiology
  • Prescription Drugs
  • Self Report
  • Time Factors

Substances

  • Prescription Drugs