Evaluation of the effect of topical application of lavender oil on autonomic nerve activity in dogs

Am J Vet Res. 2009 Jun;70(6):764-9. doi: 10.2460/ajvr.70.6.764.

Abstract

Objective: To investigate the effect of topical application of undiluted lavender oil on sympathovagal activity in dogs.

Animals: 5 healthy adult male Beagles.

Procedures: An ambulatory ECG monitor (Holter recorder) was placed on each dog (day0), and 48-hour ECGs were recorded, beginning at 8:00 the next day (day 1). Lavender oil (0.18 mL) or saline (0.9% NaCl) solution (0.18 mL) was topically applied to the inner pinnas of both ears of all dogs at 8:30, 12:00, 15:30, and 19:00 on day 2. Each trial was duplicated in each dog, with an interval of 3 to 4 days between trials. Spectral indices of heart rate variability, power in the high-frequency range, and the ratio of low-frequency to high-frequency power were calculated as an indirect estimate of autonomic nerve activity.

Results: When dogs were treated with lavender oil, the mean heart rate was significantly lower during the period of 19:00 to 22:30 on day 2, compared with the mean heart rate during the same period when dogs were treated with saline solution. On the other hand, high-frequency power during the period of 15:30 to 19:00 was significantly higher when dogs were treated with lavender oil, compared with the high-frequency power during the same period when dogs were treated with saline solution.

Conclusions and clinical relevance: The study revealed some evidence that topical application of lavender oil affected vagal activity in dogs. However, whether such an effect exists and whether lavender oil has a calming effect on dogs remains equivocal and requires additional investigation.

Publication types

  • Clinical Trial

MeSH terms

  • Administration, Topical
  • Animals
  • Autonomic Nervous System / drug effects*
  • Dogs
  • Heart Rate / drug effects
  • Lavandula
  • Male
  • Oils, Volatile / adverse effects
  • Oils, Volatile / pharmacology*
  • Plant Oils / adverse effects
  • Plant Oils / pharmacology*

Substances

  • Oils, Volatile
  • Plant Oils
  • lavender oil