The CYP2C19*17 Allele Is Associated With Better Platelet Response to Clopidogrel in Patients Admitted for non-ST Acute Coronary Syndrome

J Thromb Haemost. 2009 Aug;7(8):1409-11. doi: 10.1111/j.1538-7836.2009.03500.x. Epub 2009 May 30.

Publication types

  • Letter

MeSH terms

  • Acute Coronary Syndrome / drug therapy*
  • Aged
  • Alleles
  • Aryl Hydrocarbon Hydroxylases / genetics*
  • Blood Platelets / drug effects
  • Clopidogrel
  • Cytochrome P-450 CYP2C19
  • Female
  • Humans
  • Male
  • Middle Aged
  • Platelet Aggregation Inhibitors / pharmacology
  • Platelet Aggregation Inhibitors / therapeutic use
  • Retrospective Studies
  • Ticlopidine / analogs & derivatives*
  • Ticlopidine / pharmacology
  • Ticlopidine / therapeutic use
  • Treatment Outcome

Substances

  • Platelet Aggregation Inhibitors
  • Clopidogrel
  • Aryl Hydrocarbon Hydroxylases
  • CYP2C19 protein, human
  • Cytochrome P-450 CYP2C19
  • Ticlopidine