Abstract
The synthesis and resolution of a new axially chiral Quinazolinap ligand are reported. The application of this and other related P-N ligands to the copper catalyzed beta-borylation of alpha,beta-unsaturated esters resulted in conversions of up to 100% and ee values of up to 79%. A diastereomerically pure palladacycle of the new ligand was characterised by X-ray crystallography.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Boron / chemistry*
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Catalysis
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Copper / chemistry*
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Crystallography, X-Ray
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Esters / chemistry*
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Ligands
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Models, Molecular
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Molecular Conformation
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Nitrogen / chemistry*
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Phosphorus / chemistry*
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Quinazolines / chemical synthesis
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Quinazolines / chemistry
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Stereoisomerism
Substances
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Esters
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Ligands
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Quinazolines
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Phosphorus
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Copper
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Nitrogen
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Boron