A framework is required to guide online Interprofessional Education (IPE) (Casimiro et al., 2009). The purpose of this paper is to present such a framework: W(e)Learn. W(e)Learn can be used as a quality standard and a guide to design, develop, deliver and evaluate online IPE in both pre- and post-qualification educational settings. The framework is presented in the spirit that educational programs have defining features that, when carefully designed with the appropriate blend of factors, can help achieve desired outcomes. W(e)Learn must now be applied in various contexts to assess its constructs and its applicability.