Laserinterferometric measurements of accommodative changes in the position of an optic-shift intraocular lens

J Refract Surg. 2009 May;25(5):416-20. doi: 10.3928/1081597X-20090422-03.


Purpose: To measure optically and pharmacologically induced movement of an optic-shift intraocular lens (HumanOptics 1CU).

Methods: The change in position as well as the accommodative effect of the 1CU was determined using an anterior chamber laser interferometer (Zeiss ACMaster) in 15 eyes of 9 patients. Accommodation was induced by optical stimulus and pharmacologically by pilocarpine 2%.

Results: The mean forward movement due to optical-induced accommodation stimulation was 5 +/- 14 microm (range: -10 to + 40 microm). Pharmacological stimulation with 2% pilocarpine caused mean anterior movements of 93 +/- 162 microm (range: -321 to +/- 402 microm).

Conclusions: A maximum accommodative effect of 0.50 diopters was measured with this method. This relatively small accommodative effect of the 1CU is in agreement with other studies. Pharmacologically induced optic shift differs significantly from optically induced shift and allows no conclusion on a clinically expected accommodative effect.

MeSH terms

  • Accommodation, Ocular / physiology*
  • Aged
  • Anterior Eye Segment / physiopathology
  • Diagnostic Techniques, Ophthalmological*
  • Female
  • Humans
  • Interferometry / methods
  • Lasers
  • Lens Implantation, Intraocular
  • Lenses, Intraocular*
  • Male
  • Middle Aged
  • Miotics / administration & dosage
  • Phacoemulsification
  • Pilocarpine / administration & dosage
  • Pseudophakia / physiopathology*
  • Pupil / drug effects


  • Miotics
  • Pilocarpine