Occupation-related pigmented macules on the sole with parallel-ridge pattern on dermatoscopy

Clin Exp Dermatol. 2009 Jul;34(5):e31-3. doi: 10.1111/j.1365-2230.2008.03134.x.

Abstract

27-year-old man presented with pigmented macules on the right sole, which showed a parallel-ridge pattern on dermatoscopy. His work for a chemical company involved handling para-phenylenediamine. Histological examination of a biopsy from a lesion did not find any proliferation of atypical melanocytes. Shaving the cornified layer of the lesions with a surgical knife resulted in the disappearance of macules. We speculate that para-phenylenediamine on the sole of the patient's work boot might have become blotted to the cornified layer of the cutis. This report adds a new occupation-related differential diagnosis for skin diseases showing a parallel-ridge pattern on dermatoscopy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Chemical Industry
  • Dermatitis, Occupational / diagnosis*
  • Dermatitis, Occupational / etiology
  • Dermoscopy
  • Diagnosis, Differential
  • Foot Dermatoses / chemically induced
  • Foot Dermatoses / diagnosis*
  • Humans
  • Male
  • Melanoma / diagnosis
  • Phenylenediamines / adverse effects
  • Pigmentation Disorders / chemically induced
  • Pigmentation Disorders / diagnosis*
  • Skin Neoplasms / diagnosis

Substances

  • Phenylenediamines
  • 4-phenylenediamine