Facile ring-opening of oxiranes by H(2)O(2) catalyzed by phosphomolybdic acid

Yun Li; Hong-Dong Hao; Yikang Wu

doi:10.1021/ol900811m

Facile ring-opening of oxiranes by H(2)O(2) catalyzed by phosphomolybdic acid

Org Lett. 2009 Jun 18;11(12):2691-4. doi: 10.1021/ol900811m.

Authors

Yun Li¹, Hong-Dong Hao, Yikang Wu

Affiliation

¹ State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.

PMID: 19514796
DOI: 10.1021/ol900811m

Abstract

At ambient temperature, in the presence of catalytic amounts of phosphomolybdic acid (PMA), ethereal hydrogen peroxide reacted readily with a range of epoxides, giving corresponding beta-hydroxyhydroperoxides in high yields.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Cyclization
Ethylene Oxide / chemistry*
Hydrogen Peroxide / chemistry*
Molecular Structure
Molybdenum / chemistry*
Phosphoric Acids / chemistry*
Stereoisomerism

Substances

Phosphoric Acids
Molybdenum
Hydrogen Peroxide
Ethylene Oxide
phosphomolybdic acid