Psychiatric context of acute/early HIV infection. The NIMH Multisite Acute HIV Infection Study: IV

AIDS Behav. 2009 Dec;13(6):1061-7. doi: 10.1007/s10461-009-9585-3. Epub 2009 Jun 11.

Abstract

Acute/early HIV infection is a period of high risk for HIV transmission. Better understanding of behavioral aspects during this period could improve interventions to limit further transmission. Thirty-four participants with acute/early HIV infection from six US cities were assessed with the Mini International Diagnostic Interview, Beck Depression Inventory II, State-Trait Anxiety Inventory, Brief COPE, and an in-depth interview. Most had a pre-HIV history of alcohol or substance use disorder (85%); a majority (53%) had a history of major depressive or bipolar disorder. However, post-diagnosis coping was predominantly adaptive, with only mild to moderate elevations of anxious or depressive mood. Respondents described challenges managing HIV in tandem with pre-existing substance abuse problems, depression, and anxiety. Integration into medical and community services was associated with adaptive coping. The psychiatric context of acute/early HIV infection may be a precursor to infection, but not necessarily a barrier to intervention to reduce forward transmission of HIV among persons newly infected.

Publication types

  • Multicenter Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adaptation, Psychological
  • Adult
  • Anxiety / diagnosis
  • Anxiety / psychology*
  • Depression / diagnosis
  • Depression / psychology*
  • Female
  • HIV Infections / diagnosis
  • HIV Infections / psychology*
  • HIV Infections / transmission
  • HIV-1 / isolation & purification
  • Humans
  • Male
  • Mental Disorders / diagnosis
  • Mental Disorders / psychology*
  • Middle Aged
  • Psychiatric Status Rating Scales
  • Sexual Behavior / psychology
  • Stress, Psychological / diagnosis
  • Stress, Psychological / psychology
  • Substance-Related Disorders / diagnosis
  • Substance-Related Disorders / psychology*
  • Surveys and Questionnaires
  • United States / epidemiology

Grant support