May oxygen-ozone therapy improves cardiovascular disorders?

Cardiovasc Hematol Disord Drug Targets. 2009 Jun;9(2):78-85. doi: 10.2174/187152909788488681.


In an aging population vascular disorders well exemplified by the chronic limb ischemia, chronic heart failure, cerebral ischemia and age-related macular degeneration represent a serious medical and socio-economical problem. While there is always a not easily identifiable first pathogenic noxa, all of these diseases are characterized by ischemia, chronic inflammation and tissue degeneration. Orthodox medicine has provided several optimal drugs targeting various pathological situations but, even with their concomitant applications, it is not possible to reduce the chronic oxidative stress. Here it is proposed to associate the approach of ozonated autohemotherapy as a modifier of the biological response capable to block the pathological progress.

Publication types

  • Review

MeSH terms

  • Aged
  • Aging
  • Blood Transfusion, Autologous
  • Cardiovascular Diseases / metabolism
  • Cardiovascular Diseases / therapy*
  • Chronic Disease
  • Extremities / blood supply
  • Humans
  • Inflammation / metabolism
  • Inflammation / therapy
  • Ischemia / therapy
  • Macular Degeneration / therapy
  • Oxidative Stress
  • Oxygen / therapeutic use
  • Oxygen Consumption
  • Ozone / therapeutic use*


  • Ozone
  • Oxygen