Dopamine agonist: pathological gambling and hypersexuality

Prescrire Int. 2008 Oct;17(97):200-1.

Abstract

(1) Pathological gambling and increased sexual activity can occur in patients taking dopaminergic drugs. Detailed case reports and small case series mention serious familial and social consequences. The frequency is poorly documented; (2) Most affected patients are being treated for Parkinson's disease, but cases have been reported among patients prescribed a dopamine agonist for restless legs syndrome or pituitary adenoma; (3) Patients treated with this type of drug, and their relatives, should be informed of these risks so that they can watch for changes in behaviour. If such disorders occur, it may be necessary to reduce the dose or to withdraw the drug or replace it with another medication.

MeSH terms

  • Australia
  • Canada
  • Compulsive Behavior / chemically induced*
  • Crime
  • Dopamine Agents / adverse effects*
  • Dopamine Agonists / adverse effects*
  • Drug Overdose
  • Europe
  • Exhibitionism / chemically induced*
  • Female
  • Gambling*
  • Humans
  • Libido / drug effects*
  • Male
  • Parkinson Disease / drug therapy
  • Pituitary Neoplasms / drug therapy
  • Restless Legs Syndrome / drug therapy
  • Risk-Taking
  • Sex Offenses
  • Sexual Behavior / drug effects*
  • Theft

Substances

  • Dopamine Agents
  • Dopamine Agonists