Abstract
The antiviral activity of Panavir was studied on a model of mice infected with the strain Sofjin of tick-borne encephalitis (TBE) virus. The efficacy of Panavir was studied in the treatment of the chronic (monotherapy; 30 patients) and acute febrile and meningeal (combined therapy; n = 113) forms of TBE. Panavir was found to have a positive effect on the clinical course of TBE and the immune mechanisms of the body's protection.
Publication types
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Controlled Clinical Trial
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English Abstract
MeSH terms
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Adult
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Aged
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Animals
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Animals, Newborn
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Antibodies, Viral / blood
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Antigens / blood
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Antioxidants / administration & dosage
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Antioxidants / therapeutic use*
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Drug Evaluation, Preclinical
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Encephalitis, Tick-Borne / blood
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Encephalitis, Tick-Borne / drug therapy*
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Encephalitis, Tick-Borne / immunology
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Female
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Humans
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Injections, Intravenous
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Lymphocyte Count
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Lymphocyte Subsets / immunology
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Male
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Mice
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Middle Aged
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Probucol / administration & dosage
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Probucol / therapeutic use*
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Treatment Outcome
Substances
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Antibodies, Viral
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Antigens
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Antioxidants
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Probucol