Numerous studies have examined the effectiveness of alcohol and traffic policies in reducing automobile crashes and fatalities, but only a few have analyzed the impact of state-specific policies on motorcycle safety. Given the growing popularity and inherent safety risks of motorcycle riding, this study provides a comprehensive investigation of both fatal and non-fatal injuries. State-level longitudinal data from 1990 to 2005 are analyzed to determine how various alcohol and traffic policies impact motorcycle safety and whether there are differential effects by type of injury. The results consistently show that universal helmet laws have the most significant effect on both non-fatal and fatal injuries. Mandatory rider education programs and speed limits on rural interstates significantly impact non-fatal injuries.