Abstract
Streptococcus gordonii and Veillonella atypica, two early-colonizing members of the dental plaque biofilm, participate in a relationship that results in increased transcription of the S. gordonii gene amyB, encoding an alpha-amylase. We show that the transcription factor CcpA is required for this interspecies interaction.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Bacterial Proteins / biosynthesis
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Gene Deletion
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Gene Expression Regulation, Bacterial
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Signal Transduction*
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Streptococcus gordonii / enzymology
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Streptococcus gordonii / physiology*
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Transcription Factors / genetics
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Transcription Factors / physiology*
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Veillonella / physiology*
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alpha-Amylases / biosynthesis
Substances
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Bacterial Proteins
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Transcription Factors
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alpha-Amylases