Eruptive syringoma of the penis. A report of 2 cases and a review of the literature

Am J Dermatopathol. 2009 Jul;31(5):436-8. doi: 10.1097/DAD.0b013e3181930d93.


Syringoma exclusively located to the penis is an extraordinary rare dermatological condition, and only 6 patients with syringoma exclusively located to the penis have been published previously. Light microscopical examination of routine hematoxylin and eosin-stained sections from punch biopsies with adequate depth from 2 patients was performed. Classical syringoma was diagnosed. The lesions occurred in an eruptive fashion in both patients on the dorsal and lateral aspects of the penis shaft. There was a variation in clinical appearances ranging from yellow-white papules, a few millimeter in size to, in one of the patients, formation of several slightly elevated plaques, 10 mm in size, with a brownish-red color. We describe clinicopathological features of 2 patients with syringoma exclusively located to the penis. These are compared with all the previously published cases. Clinical and histopathological differential diagnoses are discussed, and a literature review is presented.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Humans
  • Male
  • Penile Neoplasms / pathology*
  • Penile Neoplasms / surgery
  • Sweat Gland Neoplasms / pathology*
  • Sweat Gland Neoplasms / surgery
  • Syringoma / pathology*
  • Syringoma / surgery