A case of hepatocellular carcinoma within hepatocellular adenoma in a non-cirrhotic male

Korean J Intern Med. 2009 Jun;24(2):147-52. doi: 10.3904/kjim.2009.24.2.147. Epub 2009 Jun 8.

Abstract

Hepatocellular adenoma (HA) is a benign hepatic lesion that predominantly occurs in young women. Most hepatocellular carcinomas (HCC) arise in a cirrhotic liver during the fifth or sixth decades. There have been several reported cases of HCC developing from HA in female patients. However, there are rare cases about HCC arising in HA in a non-cirrhotic male patient. We have recently encountered a 53-year-old man who had a liver mass in a non-cirrhotic liver, and the liver mass was compatible with HA on the pre-operative computed tomography. The mass was completely resected and the histopathology revealed a focus of HCC arising in HA. We report here on this case along with a brief review of the relevant literature.

Keywords: Adenoma; Hepatocellular; Hepatocellular carcinoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenoma, Liver Cell / pathology*
  • Adenoma, Liver Cell / surgery
  • Adult
  • Biopsy
  • Carcinoma, Hepatocellular / pathology*
  • Carcinoma, Hepatocellular / surgery
  • Female
  • Hepatectomy
  • Humans
  • Liver Neoplasms / pathology*
  • Liver Neoplasms / surgery
  • Male
  • Middle Aged
  • Precancerous Conditions / pathology*
  • Precancerous Conditions / surgery
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Ultrasonography
  • Young Adult