Aspergilloma formation in cavitary sarcoidosis

J Bras Pneumol. 2009 May;35(5):480-3. doi: 10.1590/s1806-37132009000500015.
[Article in English, Portuguese]


Pulmonary cavitation is rather uncommon in patients with sarcoidosis, and aspergilloma is even more uncommon in such cases. Here, we present the case of a 63-year-old female patient with cavitary lung disease who had been under treatment for TB for 9 months. A diagnosis of pulmonary sarcoidosis was established based on the fiberoptic bronchoscopy finding of noncaseating granuloma. Treatment with corticosteroids led to a dramatic improvement in symptoms. While under treatment for sarcoidosis, the patient developed an aspergilloma. She presented immediate skin test reactivity to Aspergillus fumigatus, as well as positivity for A. fumigatus serum precipitins. This is the first reported case of aspergilloma formation in a patient with cavitary sarcoidosis in India.

Publication types

  • Case Reports

MeSH terms

  • Aspergillosis / microbiology*
  • Aspergillus fumigatus* / immunology
  • Biomarkers / blood
  • Female
  • Humans
  • Lung Diseases, Fungal / microbiology*
  • Middle Aged
  • Precipitins / blood
  • Sarcoidosis, Pulmonary / complications*
  • Sarcoidosis, Pulmonary / drug therapy


  • Biomarkers
  • Precipitins