Primary angiosarcoma of the cuboidal bone: a case report

Diagn Cytopathol. 1991;7(5):520-3. doi: 10.1002/dc.2840070516.


Primary angiosarcoma of bone is a rare neoplasm. The unique cytomorphologic and ultrastructural aspects of a primary angiosarcoma of the cuboid bone diagnosed by fine-needle aspiration are presented. Smears and cell block preparations revealed single and clustered large, pleomorphic, and spindle-shaped cells with a markedly hemorrhagic background. Electron microscopy revealed characteristic features of endothelial cells including rare Weibel-Palade bodies. The clinical, cytologic, histologic, and ultrastructural aspects of the case are discussed.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biopsy, Needle
  • Bone Neoplasms / chemistry
  • Bone Neoplasms / pathology*
  • Bone Neoplasms / ultrastructure
  • Foot Diseases / pathology
  • Hemangiosarcoma / chemistry
  • Hemangiosarcoma / pathology*
  • Hemangiosarcoma / ultrastructure
  • Humans
  • Immunoenzyme Techniques
  • Male
  • Microscopy, Electron