Successful medical management of status post-Roux-en-Y-gastric-bypass hyperinsulinemic hypoglycemia

Elias Spanakis; Claudia Gragnoli

doi:10.1007/s11695-009-9888-5

Successful medical management of status post-Roux-en-Y-gastric-bypass hyperinsulinemic hypoglycemia

Obes Surg. 2009 Sep;19(9):1333-4. doi: 10.1007/s11695-009-9888-5. Epub 2009 Jun 24.

Authors

Elias Spanakis¹, Claudia Gragnoli

Affiliation

¹ Laboratory of Molecular Genetics of Complex and Monogenic Disorders, Division of Endocrinology, Diabetes and Metabolism, H044, Department of Medicine and Cellular and Molecular Physiology and Public Health Sciences, Penn State Milton S. Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA.

Abstract

Roux-en-Y gastric bypass (RYGBP) is the most commonly performed type of bariatric surgery, which is used in the treatment of obesity and type 2 diabetes. Recent case reports and case series have described a rare complication of RYGBP, status post-gastric-bypass hyperinsulinemic hypoglycemia, which was mainly managed successfully with pancreatectomy. In this letter, we describe the first successful management of status post-gastric-bypass hyperinsulinemic hypoglycemia with diazoxide.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Antihypertensive Agents / therapeutic use
Diazoxide / therapeutic use
Female
Gastric Bypass / adverse effects*
Humans
Hyperinsulinism / diagnosis
Hyperinsulinism / etiology*
Hyperinsulinism / therapy*
Hypoglycemia / diagnosis
Hypoglycemia / etiology*
Hypoglycemia / therapy*
Middle Aged
Obesity / complications
Obesity / surgery*

Substances

Antihypertensive Agents
Diazoxide