Osteoporosis in inflammatory bowel disease

Am J Med. 2009 Jul;122(7):599-604. doi: 10.1016/j.amjmed.2009.01.022.


Osteoporosis commonly afflicts patients with inflammatory bowel disease, and many factors link the 2 states together. A literature review was conducted about the pathophysiology of osteoporosis in relation to inflammatory bowel disease. Screening guidelines for osteoporosis in general as well as those directed at patients with inflammatory bowel disease are reviewed, as are currently available treatment options. The purpose of this article is to increase physician awareness about osteopenia and osteoporosis occurring in patients with inflammatory bowel disease and to provide basic, clinically relevant information about the pathophysiology and guidelines to help them treat these patients in a cost-effective manner.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Adrenal Cortex Hormones / adverse effects
  • Bone Density
  • Calcium / deficiency
  • Humans
  • Inflammation / complications
  • Inflammatory Bowel Diseases / complications*
  • Malnutrition / complications
  • Mass Screening
  • Osteoporosis / diagnosis
  • Osteoporosis / etiology*
  • Osteoporosis / therapy*
  • Risk Factors
  • Vitamin D Deficiency / complications


  • Adrenal Cortex Hormones
  • Calcium