A treatment algorithm for adult ameloblastomas according to the Pitié-Salpêtrière Hospital experience

J Craniomaxillofac Surg. 2009 Oct;37(7):363-9. doi: 10.1016/j.jcms.2009.05.001. Epub 2009 Jun 25.


During a 13-year period (from 1994 to 2007), in the Oral and Maxillofacial Surgery Department of the Pitié-Salpêtrière Hospital, 116 new cases of adult ameloblastomas, were analyzed for treatment composed against radiographic presentation, size, histological type. Follow-up and recurrence were also analyzed. Treatment was surgical consisting of enucleations (82%), segmental mandibulectomy (8.3%) resections (24.7%) 85% of them underwent reconstruction. The follow-up was documented for 97%. More than two recurrences occurred in 21% of the patients after the first enucleation: 66% with a "follicular" histological diagnosis. Lenthly, a therapeutic algorithm is suggested for adult ameloblastomas that underlines the importance of the conservative enucleation treatment as far as possible.

MeSH terms

  • Adult
  • Algorithms
  • Ameloblastoma / diagnosis
  • Ameloblastoma / therapy*
  • Clinical Protocols
  • Decision Trees*
  • Humans
  • Mandibular Neoplasms / diagnosis
  • Mandibular Neoplasms / therapy*
  • Maxillary Neoplasms / diagnosis
  • Maxillary Neoplasms / therapy*
  • Neoplasm Recurrence, Local / prevention & control*
  • Neoplasm Recurrence, Local / therapy
  • Oral Surgical Procedures / methods
  • Plastic Surgery Procedures / methods
  • Retrospective Studies
  • Severity of Illness Index
  • Treatment Outcome