Maternal bariatric surgery: adverse outcomes in neonates

Eur J Pediatr. 2010 Feb;169(2):191-6. doi: 10.1007/s00431-009-1005-1. Epub 2009 Jun 27.


Background: The obesity epidemic in developed countries has led to an increased prevalence of obese women of reproductive age. As maternal obesity has far-reaching consequences for both mother and child, the consensus is that weight loss before pregnancy will reduce obesity-related morbidity and mortality. Therefore, an increasing number of women become pregnant after undergoing obesity surgery.

Results and discussion: From the literature, data shows that perinatal outcome after bariatric surgery is generally considered as favourable for both mother and child. Only a few case reports highlight the possibility of side effects on the foetus and neonate. We report on five cases with severe intracranial bleeding, all possibly related to vitamin K deficiency following maternal bariatric surgery.

Conclusion: These reports indicate that careful nutritional follow-up during pregnancy after obesity surgery is mandatory, because nutritional deficiencies such as vitamin K deficiency can lead to life-threatening bleeding.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Bariatric Surgery / adverse effects*
  • Cerebral Palsy / etiology*
  • Fatal Outcome
  • Female
  • Follow-Up Studies
  • Humans
  • Infant, Newborn
  • Male
  • Maternal Exposure / adverse effects*
  • Obesity, Morbid / surgery*
  • Pregnancy
  • Pregnancy Complications / surgery*
  • Psychomotor Disorders / etiology*
  • Risk Factors
  • Time Factors
  • Young Adult