A genotyping exercise for pharmacogenetics in pharmacy practice

Am J Pharm Educ. 2009 May 27;73(3):43. doi: 10.5688/aj730343.


Objective: To develop a genotype exercise to improve pharmacy students' comprehension of pharmacogenetic principles that apply to patient care.

Design: Deoxyribonucleic acid (DNA) was collected during class from 10 student volunteers and subjected to genotype analysis. The results were presented to the class and discussed in the context of a patient genetic counseling session. Students completed a survey instrument regarding their attitudes toward this learning experience.

Assessment: Students indicated that the exercise engaged them with the course content and would positively influence their ability to apply pharmacogenetic principles to patient care.

Conclusion: An applied genotype exercise enhanced learning of pharmacogenetic principles. Based on these findings, conducting a genotype exercise in a large classroom setting is feasible in terms of time and expense, and meaningful in terms of student satisfaction.

Keywords: angiotensin converting enzyme; cardiovascular disease; genotype; pharmacogenetics; polymerase chain reaction.

MeSH terms

  • Curriculum
  • Education, Pharmacy*
  • Educational Measurement
  • Genotype*
  • Humans
  • Pharmaceutical Services
  • Pharmacogenetics / education*
  • Pharmacy*
  • Polymorphism, Genetic
  • Professional Practice
  • Reverse Transcriptase Polymerase Chain Reaction
  • Terminology as Topic