[Prevention of neuro- and cardiotoxic side effects of tuberculosis chemotherapy with noopept]

Klin Med (Mosk). 2009;87(5):59-62.
[Article in Russian]

Abstract

The study evaluated clinical efficiency of noopept used to prevent adverse side effects of antituberculous agents. It included 60 patients with newly diagnosed respiratory tuberculosis. Those in group 1 (n = 30) received 10 mg of noopept twice daily during the first month. The treatment promoted functional normalization of vegetative nervous system and antioxidative systems, reduced manifestations of anxiety, decreased frequency of adverse neuro- and cardiotoxic responses to antituberculous drugs.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Antitubercular Agents / adverse effects*
  • Antitubercular Agents / therapeutic use
  • Anxiety / chemically induced
  • Anxiety / drug therapy*
  • Dipeptides / therapeutic use*
  • Follow-Up Studies
  • Humans
  • Middle Aged
  • Treatment Outcome
  • Tuberculosis, Pulmonary / drug therapy*
  • Young Adult

Substances

  • Antitubercular Agents
  • Dipeptides
  • ethyl phenylacetyl-Pro-Gly