Dental and periodontal health status in children affected by cystic fibrosis in a southern Italian region

Eur J Paediatr Dent. 2009 Jun;10(2):65-8.


Aim: The aim of this study was to record the oral health status through the mean value of the DMFT/dmft index, the CPITN values and the DDE modified index in children affected by cystic fibrosis (CF).

Study design: Observational study.

Methods: A group of 54 CF patients, aged 7 to 12 years, was selected and their data were compared to those of the same age healthy control group of 101 children.

Results and statistics: CF patients showed a mean DMFT (1.5 +/- 2.17) and dmft (0.42 +/- 0.9) significantly lower than control subjects (respectively 3.70 +/- 3.92 and 2.96 +/- 3.30). Moreover, in the CF subjects a high prevalence (55.6%) of enamel defects and a better periodontal health were found, despite the low presence of calculus in both groups.

Conclusion: The low caries experience and the high prevalence of enamel defects in CF patients could be due to the metabolic disease, and above all to the long-term pharmacological therapies (antibiotics and pancreatic enzymes) that they take.

MeSH terms

  • Case-Control Studies
  • Child
  • Cystic Fibrosis / complications
  • Cystic Fibrosis / physiopathology*
  • Humans
  • Italy / epidemiology
  • Oral Health*
  • Periodontal Diseases / complications
  • Periodontal Diseases / physiopathology*
  • Tooth Diseases / complications
  • Tooth Diseases / physiopathology*