Abstract
The criteria for "biphenotypic acute leukemia" have changed with improvements in the ability to distinguish blast cells of different lineages. In her perspective on the paper by Xu et al (page 918) Dr. Béné reviews these changes, proceeding up to the most recent WHO classification. See also related review article on page 984.
MeSH terms
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Acute Disease
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Cell Differentiation
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Cell Lineage
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Chromosomes / ultrastructure
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Humans
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Immunophenotyping
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Leukemia / classification*
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Leukemia / diagnosis*
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Leukemia / genetics
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Leukemia, Biphenotypic, Acute / classification
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Leukemia, Biphenotypic, Acute / diagnosis*
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Leukemia, Biphenotypic, Acute / genetics
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Medical Oncology / methods
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Phenotype