Biphenotypic, bilineal, ambiguous or mixed lineage: strange leukemias!

Haematologica. 2009 Jul;94(7):891-3. doi: 10.3324/haematol.2009.007799.

Abstract

The criteria for "biphenotypic acute leukemia" have changed with improvements in the ability to distinguish blast cells of different lineages. In her perspective on the paper by Xu et al (page 918) Dr. Béné reviews these changes, proceeding up to the most recent WHO classification. See also related review article on page 984.

Publication types

  • Comment
  • Editorial

MeSH terms

  • Acute Disease
  • Cell Differentiation
  • Cell Lineage
  • Chromosomes / ultrastructure
  • Humans
  • Immunophenotyping
  • Leukemia / classification*
  • Leukemia / diagnosis*
  • Leukemia / genetics
  • Leukemia, Biphenotypic, Acute / classification
  • Leukemia, Biphenotypic, Acute / diagnosis*
  • Leukemia, Biphenotypic, Acute / genetics
  • Medical Oncology / methods
  • Phenotype