[Clinically relevant interaction between clopidogrel and proton pump inhibitors]

Pharm Unserer Zeit. 2009;38(4):370-1. doi: 10.1002/pauz.200990048.

[Article in German]

Authors

Susanne Alban, Theo Dingermann, Nina Griese, Wolfgang Kämmerer, Manfred Schubert-Zsilavecz, Martin Schulz, Dietmar Trenk, Petra Zagermann-Muncke

PMID: 19572357
DOI: 10.1002/pauz.200990048

No abstract available

MeSH terms

Aryl Hydrocarbon Hydroxylases / antagonists & inhibitors
Aryl Hydrocarbon Hydroxylases / metabolism
Clopidogrel
Cytochrome P-450 CYP2C19
Drug Interactions
Enzyme Inhibitors / adverse effects
Humans
Platelet Aggregation Inhibitors / adverse effects*
Platelet Aggregation Inhibitors / pharmacokinetics
Platelet Aggregation Inhibitors / therapeutic use*
Proton Pump Inhibitors / adverse effects*
Proton Pump Inhibitors / pharmacokinetics
Proton Pump Inhibitors / therapeutic use*
Ticlopidine / adverse effects
Ticlopidine / analogs & derivatives*
Ticlopidine / pharmacokinetics
Ticlopidine / therapeutic use

Substances

Enzyme Inhibitors
Platelet Aggregation Inhibitors
Proton Pump Inhibitors
Clopidogrel
Aryl Hydrocarbon Hydroxylases
CYP2C19 protein, human
Cytochrome P-450 CYP2C19
Ticlopidine