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Randomized Controlled Trial
. 2009 Aug;105 Suppl 1:S83-9.
doi: 10.1007/s00436-009-1499-5.

Efficacy and Safety of Emodepside 2.1%/praziquantel 8.6% Spot-On Formulation in the Treatment of Feline Aelurostrongylosis

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Randomized Controlled Trial

Efficacy and Safety of Emodepside 2.1%/praziquantel 8.6% Spot-On Formulation in the Treatment of Feline Aelurostrongylosis

Donato Traversa et al. Parasitol Res. .

Abstract

The objective of the present study was to evaluate the efficacy and safety of the antiparasitic spot-on formulation containing emodepside 2.1%/praziquantel 8.6% (Profender, Bayer) in the treatment of natural feline infection with the lungworm Aelurostrongylus abstrusus (Nematoda, Strongylida). Efficacy of Profender given once at the licensed dose was tested in comparison to a control oral formulation containing fenbendazole 18.75% (Panacur, Intervet) given over three consecutive days at the licensed dose. Efficacy assessment was based on larvae per gramme of faeces (LPG) counts, measured on days 28 +/- 2 following treatment and compared to counts on days -6 to -2. In total 24 cats treated either with Profender (n = 12) or with Panacur (n = 12) were included in the assessment of efficacy and safety. Mean LPG post-baseline counts (days 28 +/- 2) were 1.3 LPG for both Profender and Panacur, demonstrating similar efficacy of 99.38% for Profender and 99.29% for the control product. No treated animals showed adverse events. This trial demonstrated that both Profender spot-on formulation and oral paste Panacur are safe and effective in the treatment of aelurotrongylosis in cats. Future practical perspectives in feline medicine and the major advantages of the spot-on product compared to the oral paste are discussed.

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References

    1. Aust Vet J. 1999 Apr;77(4):229-32 - PubMed
    1. J Am Vet Med Assoc. 1987 May 15;190(10):1309-10 - PubMed
    1. J Am Vet Med Assoc. 1994 Aug 15;205(4):584-6 - PubMed
    1. Cornell Vet. 1973 Jul;63(3):483-500 - PubMed
    1. Parasitol Res. 2009 Aug;105 Suppl 1:S55-62 - PubMed

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