Use of misoprostol for management of unsatisfactory colposcopy in the adolescent: a case report and review of the literature

J Pediatr Adolesc Gynecol. 2009 Oct;22(5):e139-41. doi: 10.1016/j.jpag.2008.12.001. Epub 2009 Jul 2.


Study objective: To document the ability to use a prostaglandin analogue to achieve satisfactory colposcopy in a patient with cervical stenosis and unsatisfactory colposcopy.

Design: Case report.

Results: Satisfactory colposcopy was achieved by using 100mg of Misoprostol orally, administered the night before the planned colposcopic evaluation.

Conclusion: In the presence of persistent atypia in an adolescent female with an unsatisfactory colposcopy, consider using a prostaglandin analogue for adequate evaluation of the endocervix, prior to proceeding with an ablative or excisional therapy.

Publication types

  • Review

MeSH terms

  • Administration, Intravaginal
  • Adolescent
  • Cervix Uteri / drug effects
  • Cervix Uteri / pathology*
  • Colposcopy*
  • Constriction, Pathologic
  • Dilatation / methods
  • Female
  • Humans
  • Misoprostol / administration & dosage
  • Misoprostol / therapeutic use*
  • Oxytocics / administration & dosage
  • Oxytocics / therapeutic use*
  • Preoperative Care
  • Reoperation
  • Uterine Cervical Dysplasia / surgery
  • Uterine Cervical Neoplasms / surgery
  • Vaginal Smears


  • Oxytocics
  • Misoprostol