The multi-scale microstructure of a lotus leaf is rendered non-wetting by micro-protrusions and nano-hairs present on its surface. The mechanical properties of the surface become important since the water droplet has to be supported on the micro-protrusions without wetting the surface. Current work correlates the non-wetting behavior of the lotus leaf with its mechanical properties (Young's modulus and critical flexing stress) and areal spread of micro-protrusions on the leaf surface. Quasistatic nanoindentation of nano-hairs on the lotus leaf surface has shown a variation of elastic modulus between 359 and 870 MPa, which in turn dictates the critical flexing strength and consequent non-wetting. Computational fluid dynamics modeling is utilized to correlate wetting phenomena with the areal spread of micro-protrusions. A qualitative model is proposed for the way nature has chosen to render the lotus leaf surface non-wetting.