Highly asymmetric cobalt-catalyzed aziridination of alkenes with trichloroethoxysulfonyl azide (TcesN3)

Velusamy Subbarayan; Joshua V Ruppel; Shifa Zhu; Jason A Perman; X Peter Zhang

doi:10.1039/b905727g

Highly asymmetric cobalt-catalyzed aziridination of alkenes with trichloroethoxysulfonyl azide (TcesN3)

Chem Commun (Camb). 2009 Jul 28:(28):4266-8. doi: 10.1039/b905727g. Epub 2009 Jun 11.

Authors

Velusamy Subbarayan¹, Joshua V Ruppel, Shifa Zhu, Jason A Perman, X Peter Zhang

Affiliation

¹ Department of Chemistry, University of South Florida, Tampa, FL 33620-5250, USA.

PMID: 19585042
DOI: 10.1039/b905727g

Abstract

A Co(II)-based catalytic system has been developed for asymmetric aziridination of alkenes with trichloroethoxysulfonyl azide (TcesN3) under mild conditions, forming the corresponding N-Tces-aziridines in high yields and excellent enantioselectivities.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Alkenes / chemistry*
Azides / chemistry*
Aziridines / chemistry*
Catalysis
Cobalt / chemistry*

Substances

Alkenes
Azides
Aziridines
trichloroethoxysulfonyl azide
Cobalt