Efficacy of chemical and/or surgical therapy against condylomata acuminata: a retrospective evaluation

Int J STD AIDS. Sep-Oct 1991;2(5):333-8. doi: 10.1177/095646249100200504.

Abstract

In order to estimate treatment resistance of condylomas, standardized records of 230 males aged 17-80 years (mean 27) attending at an STD clinic were analysed retrospectively. Anal warts occurred in 38 (17%) men; in 19 (50%) intranal warts were extensive enough to require further referral to the Department of Surgery. Urinary meatal warts occurred in 30 men; 9 of them (30%) were referred to the Department of Urology. The remaining 202 (88%) men were treated in the STD clinic with simple surgery and/or home-treatment with 0.5% podophyllotoxin-ethanol twice a day for one or more 3 day sessions. After a follow-up of at least one year, 46 (23%) patients still had condylomas. However, 77 (49%) of the remaining 156 men were cured after a single therapeutic session, and after 1-4 sessions the cumulative cure rate was 77%.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anus Neoplasms / drug therapy
  • Anus Neoplasms / epidemiology
  • Anus Neoplasms / surgery*
  • Combined Modality Therapy
  • Condylomata Acuminata / drug therapy
  • Condylomata Acuminata / epidemiology
  • Condylomata Acuminata / surgery*
  • Follow-Up Studies
  • Genital Neoplasms, Male / drug therapy
  • Genital Neoplasms, Male / epidemiology
  • Genital Neoplasms, Male / surgery*
  • Humans
  • Male
  • Middle Aged
  • Podophyllotoxin / administration & dosage
  • Podophyllotoxin / therapeutic use*
  • Referral and Consultation / statistics & numerical data
  • Retrospective Studies
  • Risk Factors
  • Sexual Behavior
  • Sweden / epidemiology
  • Treatment Outcome

Substances

  • Podophyllotoxin