Abstract
Intravascular large B-cell lymphoma (IVBCL) is a rare malignant neoplasm characterized by the proliferation of large B cells within the blood vessels. The disease can be limited to the skin, but involvement of other organs is common. We report a case of cutaneous IVBCL in a 62-year-old man with minimal histological changes in contrast to prominent skin lesions. The patient was successfully treated with rituximab in combination with CHOP chemotherapy.
Copyright 2009 S. Karger AG, Basel.
MeSH terms
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Antibodies, Monoclonal / administration & dosage*
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Antibodies, Monoclonal, Murine-Derived
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Biopsy
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Cyclophosphamide / administration & dosage
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Doxorubicin / administration & dosage
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Humans
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Lymphoma, Large B-Cell, Diffuse / diagnosis
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Lymphoma, Large B-Cell, Diffuse / drug therapy*
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Lymphoma, Large B-Cell, Diffuse / pathology*
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Male
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Middle Aged
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Prednisolone / administration & dosage
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Rituximab
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Skin Neoplasms / diagnosis
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Skin Neoplasms / drug therapy*
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Skin Neoplasms / pathology*
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Thoracic Wall / pathology
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Treatment Outcome
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Vascular Neoplasms / diagnosis
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Vascular Neoplasms / drug therapy*
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Vascular Neoplasms / pathology*
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Vincristine / administration & dosage
Substances
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Antibodies, Monoclonal
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Antibodies, Monoclonal, Murine-Derived
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Rituximab
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Vincristine
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Doxorubicin
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Cyclophosphamide
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Prednisolone