Three new vanilloid derivatives from the stems of Baccaurea ramiflora

Planta Med. 2010 Jan;76(1):88-90. doi: 10.1055/s-0029-1185901. Epub 2009 Jul 9.

Abstract

Three new (1-3) and four known (4-7) compounds were isolated from the stems of Baccaurea ramiflora. By analysis of 1D, 2D NMR, and MS data, the new compounds were identified as 4'-O-(6- O-vanilloyl)-beta-D-glucopyranosyl tachioside D (1), 6'-O-vanilloylpicraquassioside D (2), and 6'-O-vanilloylicariside B(5) (3). Compound 1 exhibited significant DPPH radical-scavenging activity, with an IC(50) value of 36.9 microM, while compound 4 revealed weak antioxidant activity against H (2)O(2)-induced impairment in PC12 cells.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antioxidants / isolation & purification*
  • Antioxidants / pharmacology
  • Biphenyl Compounds
  • Disaccharides / isolation & purification*
  • Disaccharides / pharmacology
  • Hydrogen Peroxide
  • Inhibitory Concentration 50
  • Magnoliopsida / chemistry*
  • Monosaccharides / isolation & purification*
  • Monosaccharides / pharmacology
  • PC12 Cells
  • Picrates
  • Plant Extracts / chemistry*
  • Plant Extracts / pharmacology
  • Plant Stems
  • Rats

Substances

  • 4'-O-(6- O-vanilloyl)-beta-D-glucopyranosyl tachioside D
  • 6'-O-vanilloylicariside B5
  • 6'-O-vanilloylpicraquassioside D
  • Antioxidants
  • Biphenyl Compounds
  • Disaccharides
  • Monosaccharides
  • Picrates
  • Plant Extracts
  • Hydrogen Peroxide
  • 1,1-diphenyl-2-picrylhydrazyl